Immunomodulatory Biomaterials to Promote Early Transplant Integration and Wound Healing
14 Jan 2020 | Contributor(s):: Sok, Mary Caitlin P.
Advisors: Edward A Botchwey, Andrew Adams, Andrew Neish, Julia Babensee, Krishnendu RoyOngoing advances in transplantation surgical techniques, together with improvements in immunosuppression regimens, have greatly reduced the rate of postoperative morbidity and graft loss. Despite these...
Hydrogel Engineering for Enhancing Vascularization and Augmenting Immunomodulation of Encapsulated Mesenchymal Stem Cells
21 Aug 2019 | Contributor(s):: Garcia, Jose
Advisors: Andres J Garcia, Robert E Guldberg, Edward Botchwey, W. Robert Taylor, Alberto Fernandez-NievesSince the discovery of adult human mesenchymal stem cells in the late 1900's, the potential of utilizing these cells in the clinic for cell-therapy applications has been an ever-present goal....
Immunomodulatory Biomaterials for Skeletal Muscle Repair
29 May 2019 | Contributor(s):: San Emeterio, Cheryl Lau
Advisors: Edward BotchweyThough skeletal muscle possesses robust potential for healing after injury, large volumetric wounds that occur during combat, accidents or surgical resection often do not heal completely, resulting in fibrotic scarring and limited range of motion. Current standard of care...