Toward Contextualizing Receptor-Ligand Interactions in T Cells and Macrophages
20 May 2020 | Contributor(s):: Nik Rushdi, Nik Muaz
Advisors: Cheng Zhu, Antony Chen, Lou Ann Brown, Melissa Kemp, Khalid SalaitaT cell mediated immune response to pathogens is triggered by the T cell receptor (TCR) engaging with peptide-major histocompatibility complex (pMHC), which can be facilitated by the CD4 coreceptor. However, detecting...
Immunomodulatory Biomaterials for Skeletal Muscle Repair
29 May 2019 | Contributor(s):: San Emeterio, Cheryl Lau
Advisors: Edward BotchweyThough skeletal muscle possesses robust potential for healing after injury, large volumetric wounds that occur during combat, accidents or surgical resection often do not heal completely, resulting in fibrotic scarring and limited range of motion. Current standard of care...
Fc Coated Micro/Nanoparticles for Humoral Immune System Modulation
07 Jan 2016 | Contributor(s):: Pacheco, Patricia Marie
Advisors: Todd Sulchek, Julia Babensee, Julie Champion, Andres J. Garcia, David WhiteThe body's humoral immune response plays a larger role in the body's defenses beyond screening for invading pathogens. Modulation of this response is also vital for tissue regeneration, drug delivery, and vaccine...